I don't really see any difference (strenght wise) as there isn't much movement there.
Does anyone know of wrist pin failures?? There's a huge amoung of oil there already that the oil rings provide.
The GMC engines were hugh & built 'tougher' for that (post Korean war) era. Remember they had to compete with Ford, Dodge, International and Chevrolet.
I guess (it wouldn't hurt) for an 'all out' racing engine.